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Showing posts with label magnetic resonance imaging. Show all posts
Showing posts with label magnetic resonance imaging. Show all posts

Saturday, April 11, 2009

Magnetic Resonance Imaging (MRI): Better Breast Cancer Early Detection Tool?

Part [1] [2] [3] 4

A new kind of MRI (magnetic resonance imaging) machine helps doctors diagnose breast cancer earlier. Patients lie on their stomach and their breasts are placed in two coils, which focus radio waves and allow for more complete images that give a three-dimensional look inside the breast.

Two-hundred thousand women will be diagnosed with breast cancer this year in the United States.



Mammograms, however, may not be the best way to detect it. Now, there's a new test to help doctors pinpoint and treat breast cancer.

Suzette Lipscomb knows how to get the most out of every moment and she plans to share most of those moments with her little girl, Ava. "I always wanted a little girl, but I was a little afraid that I may pass on some type of tendency toward the disease," Suzette says.

The disease she feared? Breast cancer.

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Her grandmother beat it and so did she. It wasn't easy though, during her battle she was forced to make a difficult decision. Suzette says, "I was trying to make a decision as to whether or not to remove both my breasts."

Richard Reitherman, a breast radiologist at CAD Imaging Sciences in White Plains, N.Y., used the new CAD-sciences breast imaging system to help decide which treatment would work best.

For the test, patients lie on their stomach with their breasts in two coils, which help focus radio waves for more complete images.

"She and her surgeon know exactly how big the tumor is, so it gives her the best treatment," Dr. Reitherman says. For Suzette it showed her second breast was clear.

A dye injected into the patient helps pinpoint cancer and if chemotherapy treatments are working. In the scan, the red areas are cancer -- cancer that was missed in a mammogram.

In fact, 20 percent of women who don't have the CAD-sciences MRI will need a second surgery, something Suzette was able to avoid.

"I feel like the luckiest woman alive that not only did I have my cancer caught early enough that I'm alive, but that I was able to have a child," Suzette says.

Not all women are candidates for this CAD-sciences MRI. It's used for women who have already been diagnosed and need to know a course of action. It's also used for women who are high risk and have a family history of the disease. The procedure takes about 30 minutes; results are available 15 minutes later.



BACKGROUND: -- Women have a new imaging tool set to help diagnose breast cancer. The 3TP method generates a unique color-coded map by measuring changes (color and intensity) in contrast agent concentration in normal and cancerous tissues over time. It provides information that is not readily available from traditional mammography or MRI. In addition, the 3TP system is ergonomically designed to be comfortable for the patient, regardless of breast size.

HOW M.R.I. WORKS: -- Magnetic resonance imaging uses radiofrequency waves and a strong magnetic field instead of X-rays to provide clear and detailed pictures of internal organs and tissues. These radio waves are directed at protons in hydrogen atoms -- one of the most abundant atoms in the human body, because of the body's high water content. The waves "excite" the protons, and when they "relax," they emit strong radio signals. A computer can turn those signals into a high-contrast image showing differences in the water content and distribution in various bodily tissues. It is becoming increasingly popular as an alternative to traditional X-ray mammography for the early diagnosis of breast cancer because women aren't exposed to the same radiation they experience with X-rays.

ABOUT BREAST CANCER: -- Breast cancer is a type of cancer in which cells in the breast become abnormal and grow and divide uncontrollably, eventually forming a mass called a tumor. Some tumors are benign, meaning that they do not invade other types of tissue, although if they become big enough, they can interfere with some bodily functions, such as the flow of blood or urine. Malignant tumors have cells that can invade nearby tissues. When a cancer "metastasizes," cells from the original tumor break off and travel to other parts of the body via the blood or lymph systems. More than 75 percent of breast cancers begin in the milk ducts within the breast. The next most common site is in the glandular tissue that makes the milk.

DO-IT-YOURSELF BREAST EXAM: -- Although it is not a substitute for regular tests by your doctor, women can perform a basic breast self-exam at home. In fact, more than 90 percent of all breast lumps are found by the women themselves. Breast tissue is shaped like a comma with the tail curving up toward the armpit, and normally has a lumpy feel. Because hormones can affect the breast tissue, the best time to examine your breasts is a few days after
your period ends, when hormone levels are stable.

[SOURCE: Science Daily]
Part [1] [2] [3] 4


Tuesday, October 7, 2008

How To Win Against Acute Renal Failure (2)

Part 1 Part 2

Risk Factors

Conditions that increase your risk of acute kidney failure include:

  • Advanced age
  • Chronic infection
  • Diabetes
  • High blood pressure
  • Heart failure
  • Various blood disorders
  • Immune disorders, such as lupus, IgA nephropathy and scleroderma
  • Kidney diseases
  • Liver diseases
  • Prostate gland enlargement
  • Bladder outlet obstruction

Acute kidney failure almost always occurs in connection with another medical condition or event. In fact, most people who experience acute kidney failure are already in the hospital for other reasons, such as severe injury, complicated surgery or overwhelming infection.

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Tests and Diagnosis

When signs and symptoms point to acute kidney failure, blood and urine tests pin down the diagnosis. Changes associated with acute kidney failure include:

  • Daily urine output usually falls to less than 2 cups (500 milliliters).

  • Blood urea and creatinine levels rise rapidly.

  • Blood electrolyte concentrations — levels of minerals such as sodium, potassium and calcium that regulate fluid balance and muscle function, plus many other vital processes — become unstable, causing swelling (edema) and lung congestion.

  • Blood potassium, in particular, rises rapidly, often to life-threatening levels.

Ultrasound is the imaging test most commonly used in diagnosing kidney failure, but your doctor may also order an abdominal computerized tomography (CT) or magnetic resonance imaging (MRI) scan.

In a few cases, your doctor may remove a small sample (biopsy) of kidney tissue and send it to a laboratory for microscopic examination to identify the cause of acute kidney failure.

Complications

The sooner the cause of your acute kidney failure is resolved, the more likely you'll be to recover your kidney function.

Occasionally, acute kidney failure causes permanent loss of kidney function, or end-stage renal disease. People with end-stage renal disease require either permanent dialysis — a mechanical filtration system for removing toxins and waste from your body — or a kidney transplant to survive.

Acute kidney failure may be fatal. Death rates are highest when the kidneys fail after surgery or trauma or in the context of severe, chronic medical problems.

Other factors that can adversely affect the outcome of acute kidney failure include multiorgan failure, multiple blood transfusions, a recent history of stroke or heart attack, or a postoperative stroke, advanced age, infection, gastrointestinal bleeding and pre-existing malnutrition.

Treatments and Drugs

The first goal is to treat the illness or injury that originally damaged your kidneys. Once that's under control, the focus will be on preventing the accumulation of excess fluids and wastes in your blood while your kidneys heal. This is best accomplished by limiting your fluid intake and following a high-carbohydrate, low-protein, low-potassium diet.

Your doctor may prescribe calcium, glucose or sodium polystyrene sulfonate (Kayexalate) to prevent the accumulation of high levels of potassium in your blood. Too much potassium in the blood can cause dangerous irregular heartbeats (arrhythmias).

Dialysis

Most of the time, you also need to undergo temporary hemodialysis — often referred to simply as "dialysis" — to help remove toxins and excess fluids from your body while your kidneys heal. Dialysis, which is a mechanical way of filtering waste from your blood, is an imperfect but lifesaving substitute for kidney function.

In acute kidney failure, dialysis is usually done at a hospital or dialysis center, not at home. The treatment relies on an artificial kidney (dialyzer) to take over kidney function.

Blood is pumped out of your body to the artificial kidney through one of two routes — a catheter placed surgically in one of your main blood veins, or a surgically created junction between a vein and artery in your arm.

Inside the artificial kidney, your blood moves across membranes that filter out waste before being returned to your body. Less than 1 cup (237 milliliters) of blood is outside your body in the dialyzer and tubing at any one time.

Hemodialysis

Prevention

Acute kidney failure is often impossible to prevent. But you may reduce your risk by following these suggestions:

  • Don't abuse alcohol or drugs, including over-the-counter pain medications such as aspirin, acetaminophen and ibuprofen.
  • Avoid long-term exposure to heavy metals, such as lead, as well as to solvents, fuels and other toxic substances.

Carefully follow all of your doctor's recommendations for managing any chronic medical condition that increases your risk of kidney failure.

If you're at high risk of kidney damage induced by contrast dye used for certain X-rays — for example, if you have diabetes or multiple myeloma — your doctor may prescribe a dose of acetylcysteine before the procedure. This medicine can help prevent acute kidney failure under these circumstances.

[SOURCE: Mayo Clinic.com ]
Part 1 Part 2

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